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CLK2 inhibitor Indazole1
CAS No. ——
CLK2 inhibitor Indazole1( Indazole1 )
Catalog No. M16934 CAS No. ——
CLK2 inhibitor Indazole1 is a novel potent, selective inhibitor of CLK2 with IC50 of 2.7 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameCLK2 inhibitor Indazole1
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NoteResearch use only, not for human use.
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Brief DescriptionCLK2 inhibitor Indazole1 is a novel potent, selective inhibitor of CLK2 with IC50 of 2.7 nM.
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DescriptionCLK2 inhibitor Indazole1 is a novel potent, selective inhibitor of CLK2 with IC50 of 2.7 nM, 60-fold selectivity over PKA and >600-fold selectivity over a panel of 34 kinases; rescues spine density in mouse brain slices at 300 nM; displays 96-fold more potent than TG003 in the CLK2 Caliper assay.
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In Vitro——
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In Vivo——
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SynonymsIndazole1
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PathwayCell Cycle/DNA Damage
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TargetCLK
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RecptorCLK
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight324.428
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Molecular FormulaC19H24N4O
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(S)-4-methyl-1-((5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl)oxy)pentan-2-amine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lerchner AM, et al. ChemMedChem. 2018 Jul 9. doi: 10.1002/cmdc.201800344.
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